On the basis of comprehensive tumor treatment, limb preservation therapy for malignant bone tumors of the limbs has become the main development direction of surgical treatment for malignant bone tumors of the limbs due to the continuous application of new materials and technologies, which has broken through some contraindicated scope of previous surgeries. It is generally believed that only patients with bone tumors meeting the following conditions can undergo limb-preserving surgery: 1. basic maturity of skeletal development, epiphysis closed or tending to be closed; 2. stage IIA of Enneking stage and stage IIB tumor with good response to chemotherapy; 3. major nerves and blood vessels not involved; 4. expected postoperative limb function better than prosthesis; 5. estimated local recurrence rate and metastasis rate not higher than amputation patients; 6. The tumor can be extensively resected with sufficient local skin and soft tissue coverage; 7. The patient requires limb preservation. In recent years, with the improvement of surgical techniques and the advancement of reconstruction materials and methods, the indications for limb preservation surgery have been expanded, and some scholars believe that those with isolated metastases of stage III bone tumors that can be radically treated and those with pure vascular involvement that can be replaced by artificial vessels are not absolute contraindications to limb preservation surgery. However, the effect of limb-preserving surgery for bone tumor patients is obviously related to the nature and scope of the tumor itself, so it is necessary to strictly control the indications for limb-preserving surgery.