Uremia is an advanced manifestation of various types of kidney diseases and can be categorized into primary uremia and secondary uremia. Any disease that damages the kidneys may cause renal failure, which may further develop into uremia if not interfered. 1. Primary uremia: Chronic glomerulonephritis, chronic pyelonephritis, polycystic kidney disease, glomerular arteriosclerosis and other primary renal diseases can cause primary uremia if they develop further, which is a result of the natural development of the disease. 2. Secondary uremia: Non-renal diseases such as hypertension, diabetes mellitus, allergic purpura, systemic lupus erythematosus, multiple myeloma, etc., may also lead to impaired renal function, resulting in secondary renal disease, which will ultimately lead to the emergence of secondary uremia. It is important to note that if the patient appears to have uremia, he should go to the hospital in time to find out the cause of the disease, and actively treat it, so as not to delay the condition.