(Disclaimer: This article is only for scientific purposes, in order to protect the privacy of patients, the relevant information in the following content has been processed) Abstract: This article describes a middle-aged male patient, 3 years ago, lower limb numbness, cold and pain, at the same time, there is intermittent claudication, 1 month ago, the symptoms significantly worsened, intermittent claudication distance is significantly reduced, and after admission to the hospital to improve the relevant examination, it is clear that the lower limb arterial lumen of varying degrees of stenosis. According to the characteristics of the lesion, the patient was recommended to use minimally invasive interventional therapy – drug balloon dilatation of stenotic arteries. After the operation, the patient’s blood flow was smooth. After six months of follow-up, the symptoms of the lower limbs disappeared, and the color ultrasound suggested that the blood flow of the lower limb arteries was smooth, and the effect was remarkable. Basic information] Male, 57 years old [Disease type] Lower limb arterial stenosis [Hospital] Liaoning Provincial People’s Hospital [Time of consultation] December 2021 [Treatment plan] Drug balloon dilatation + medication (aspirin + beclomethasone sodium) [Treatment cycle] Hospitalization 7 days, 1 month, half a year after the outpatient follow up [Effect of treatment] The patient’s symptoms of ischemia of the lower limbs disappeared after the operation, and after six months of follow-up blood flow was smooth. I. Initial Consultation In December 2021, a 57-year-old male patient came to our clinic with the main complaint of “right lower limb pain, numbness with coldness for 3 years, aggravated for 1 month”. 3 years ago, the patient had right lower limb pain and coldness with numbness without obvious triggers, and intermittent claudication, with a claudication distance of 100 meters. The symptoms gradually worsened, and the distance of intermittent claudication was shortened to 50 meters 1 month ago. The ultrasound of lower limb arteries in the outpatient clinic suggested that: atherosclerosis of both lower limbs, right lower limb arteries with different degrees of stenosis, local occlusion. When asked about his medical history, the patient had hypertension, diabetes mellitus, and old cerebral infarction, and had a history of smoking for more than 30 years, with 2-3 boxes/day. Recently, his diet and sleep were fine, his bowel movements were normal, and he had no significant weight loss. After admission, the patient was admitted to the hospital to improve the relevant examinations, because the patient has more basic diseases and poor compliance, so the relevant departments were asked to regulate the blood pressure and blood glucose, in order to further assess the degree of ischemia of the patient’s lower limb arteries, lower limb arterial CTA suggests that: right iliac artery, superficial femoral artery, popliteal artery of varying degrees of stenosis, and right popliteal artery intermittent imaging. The patient was considered to have atherosclerosis of the lower limb arteries with lumen narrowing, insufficient blood flow, and ischemia of the distal limb. Because the patient’s current intermittent claudication distance is short, belonging to the severe ischemia, considering the patient’s long-term smoking, the combination of hypertension, diabetes mellitus, and poor vascular conditions, the patient was recommended to undergo minimally invasive endoluminal treatment. Since the patient was at risk of reocclusion after the procedure, pharmacologic balloon dilatation was preferred to avoid the problem of restenosis after stenting. After intraoperative pharmacologic balloon dilatation, the vessel lumen was significantly enlarged, blood flow was accelerated, and there was no significant elastic retraction or clipping, so remedial stent implantation was not necessary. The patient was discharged from the hospital after 1 week with the antiplatelet drug aspirin and the vasodilator drug beclomethasone sodium. Third, the therapeutic effect The patient’s postoperative effect was remarkable, with the disappearance of lower limb pain and coldness, and the intermittent claudication distance improved significantly. The right lower limb femoral artery, popliteal artery and posterior tibial artery pulsation could be touched. Postoperative numbness was gradually relieved, and no lower limb pain was observed after discharge from the hospital after walking a distance of more than 600 meters. One month after discharge, half a year outpatient review ultrasound, the patient can be seen in the lower limb blood flow, inter-claudication distance of 600-800 meters, no obvious lower limb numbness, cold, cold feeling at rest. Fourth, the precautions For this case, the patient through the drug balloon dilatation and part of the drug treatment of arterial blood flow, the effect is remarkable, for this reason feel very pleased. The following are for personal life and postoperative precautions: 1, arterial stenosis is mostly the basis of atherosclerosis, therefore, patients also need to be absolutely good habits after treatment, including absolute smoking cessation, low-salt and low-fat diet, eat more fresh fruits and vegetables, more sports, functional exercise. Control blood pressure, blood sugar, blood fat. 2, arterial stenosis interventional surgery, there is a risk of recurrence, after surgery is not a one-off, the need for patients to regular review, follow the doctor’s instructions to eat a good oral medication, such as reappearance of lower limb arterial ischemia, the need to go to the hospital in a timely manner to deal with the symptoms. V. Personal perception Arterial stenosis is one of the most common arterial stenosis diseases in the clinic. In this case, the patient’s lower limb arterial stenosis caused by lower limb arterial ischemia, limb numbness, coldness, pain, intermittent claudication and other appearances, but also a large number of people. Arterial stenosis is mostly plaque formation on the basis of atherosclerosis and thickening of the lining, so the control of diet and exercise, and absolute abstinence from smoking and alcohol are particularly important for patients with arterial stenosis. In addition, arterial stenosis is not an arterial thrombus, and it is not possible to completely remove the endothelium or plaque that causes the blockage. Therefore, do not believe in irregular and inaccurate treatments and claims such as plaque dissolution, and always go to a specialized vascular surgery department.