WHO regulations stipulate that antipyretic agents should be applied when the anal temperature is above 39 degrees, and any infant under 2 months of age with an anal temperature of 38.5 degrees should be considered to have an infection or serious infection present, and anti-infective treatment should be administered first, without advocating the use of antipyretic agents first. In children over 2 months of age, once the decision to treat fever has been made, appropriate antipyretic methods should be selected. Traditionally, this includes both pharmacologic and non-pharmacologic aspects. Nonpharmacologic treatment should be chosen first. The WHO does not advocate the traditional method of cooling fever with cold, warm water or alcohol baths, which has been shown to violate physiological mechanisms. Cold and warm water baths can aggravate pneumonia and other diseases, while alcohol baths can be absorbed through the skin and cause symptoms of alcoholism in infants. The safe and effective method is to rely on medication, and the WHO recommends paracetamol orally and every 4 hours if the fever does not subside. In recent years, some scholars advocate the application of new non-steroidal anti-inflammatory drugs, such as ibuprofen, naproxen (this drug has a lot of side effects and is not recommended), because most fevers are related to endogenous pyrogens. Endogenous pyrogens can produce a variety of inflammatory mediators, and NSAIDs can reduce the production of inflammatory mediators. The antipyretic effect of naproxen is 22 times that of aspirin, the anti-inflammatory effect is 11 times that of botrytisine, and the analgesic effect is 7 times that of aspirin, which is a highly effective antipyretic and analgesic drug at a dose of 8-10 mg/kg per dose. myeloablative antipyretic agents are not recommended at present, especially analgesic or compound aminopyrine, which can produce acute granulocyte deficiency after use, which is fatal and has a much higher chance than chloramphenicol. Commonly used methods and standards for measuring body temperature Normal body temperature in children is often measured by anal temperature of 36.5 to 37.5°C and axillary temperature of 36 to 37°C. Usually, the axillary temperature is 0.2 to 0.5℃ lower than the oral temperature (under the tongue), and the anal temperature is about 0.5℃ higher than the axillary temperature. Although the anal temperature is more accurate than the axillary temperature, the axillary temperature is often used for various reasons. If the axillary temperature exceeds 37.4℃ and the body temperature fluctuates by more than 1℃ during the day, it can be considered as fever. The so-called low fever refers to axillary temperature of 37.5～38℃, moderate fever of 38.1-39℃, high fever of 39.1-40℃, and ultra-high fever of 41℃ or more. A fever lasting more than two weeks is considered prolonged fever.