Rotavirus antigen is not a vaccine; they are different concepts. Rotavirus antigen is a substance that triggers the production of antibodies to rotavirus by stimulating a cellular response in the body. If rotavirus antigen is present in the body, rotavirus infection is considered to have occurred, and after treatment, the antigen may induce the body to produce antibodies, or it may be completely killed, and the antigen does not have the function of preventing disease. On the other hand, a rotavirus vaccine is a vaccine in which the virus is extracted and cultivated to stimulate the immune system to produce antibodies after entering the human body, thus preventing the disease. The rotavirus is the antigen, and the vaccine is prepared on the basis of the virus, retaining the immunogenicity. Therefore, the principles and concepts of the two are different and should not be confused. If rotavirus antigen is detected, it is recommended to follow the doctor’s instructions for treatment.