As people become more health conscious, routine annual medical checkups can be of great help in detecting physical ailments. Gastroscopy is a great advantage for diagnosing stomach and duodenal diseases. However, when people hear about gastroscopy, they think of a thick black tube going down the throat and into the stomach, which gives them a “shiver” feeling and creates fear. This is where a painless gastroscopy can be advantageous. The beautiful nurse practitioner will first give us a hangnail, and then the handsome anesthesiologist will push propofol anesthesia (commonly known as “milk”), so we will soon fall asleep and have a beautiful sleep, and wake up when the gastroscopy is over. This is a painless gastroscopy. Although painless gastroscopy is largely safe, there are some risks involved. This requires us to pay attention to the following matters when performing painless gastroscopy: 1. Fasting and drinking for more than 6 hours before the examination, accompanied by a family member is required. 2. In the early stage of waking up, the patient will have a transient light-headedness and often uncoordinated movements, and will easily fall or fall out of bed, therefore, a family member should accompany the patient and rest in the examination room for about half an hour, and leave only after there is no abnormality to avoid accidents, and someone should accompany the patient within 2 hours after the examination. 3. Do not drink alcohol, do not drive, do not manipulate complex machines or instruments, do not participate in work discussions and decisions within 24 hours after the examination. 4. Do not drink alcoholic beverages within 2 hours after the examination, start with a small amount of light liquid diet and gradually increase the amount to avoid stomach distension and nausea or vomiting. 5. No acute upper respiratory tract infectious diseases and no serious cardiopulmonary system diseases occurred one week before the examination. 6. Routine electrocardiogram and blood pressure monitoring are required before the examination. Knowing all these, gastroscopy becomes very easy!