It is not recommended to drink coffee while taking cold medicine. Because cold medicines contain many ingredients such as acetaminophen, caffeine and amantadine, and coffee contains a lot of caffeine, if you take cold medicines and drink coffee at the same time, it will aggravate the body’s intake of caffeine. If it exceeds the normal range of caffeine intake, it will aggravate its side effects, which is not good for the body. Drinking coffee will also stimulate the nerves and intestines, speed up respiration, blood circulation and urination, speed up the metabolism of the drug, reduce the role of the drug in the body, and make the drug less effective. So during the period of taking cold medicine, it is not recommended to drink coffee, so as not to lead to the aggravation of cold. If necessary, go to the hospital in time to consult the treatment.