Sodium bicarbonate tablets should not be taken together with phenobarbital, hydrochlorothiazide, amphetamine, prednisone and other drugs. 1. Sodium bicarbonate tablets can not be combined with phenobarbital, the combination will accelerate the excretion of acidic drugs, resulting in reduced efficacy. 2. Sodium bicarbonate tablets can not be combined with hydrochlorothiazide, the combination will occur when the increase in hypochlorhydria alkalosis. 3. Sodium bicarbonate tablets can not be combined with amphetamine, sodium bicarbonate tablets can increase the efficacy of alkaline drugs amphetamine, causing toxic reactions. 4. Sodium bicarbonate tablets can not be combined with prednisone, the combination of easy to occur hypernatremia and edema. When taking sodium bicarbonate tablets, it should be taken under the guidance of a doctor, do not self-medication to avoid adverse effects.