Numbness of the lower limbs caused by comminuted fracture of the middle and lower part of the right femur is mostly considered to be caused by nerve injury, and it is recommended to have a further examination first, and then give treatment after a clear diagnosis. Traumatic femur fracture, resulting in numbness of the lower limbs, may be caused by local soft tissue swelling and compression of the nerve, or direct contusion of the nerve, or even rupture of the nerve, it is recommended to carry out a local ultrasound, electromyography of the lower limbs, and an MRI examination of the right lower and middle femur (including the fibular head of the knee), to clarify which nerve is injured (sciatic nerve, common peroneal nerve, or tibial nerve), as well as the extent of the damage to the nerves. If the nerve is compressed, it is recommended to perform tibial tuberosity bone traction, elevate the lower limbs, and take medication to reduce swelling (Panlongqi tablets), and apply ice to the fracture site at an early stage, followed by alternating hot and cold compresses to promote blood circulation and accelerate the reduction of swelling. If the nerve is contused, it can be observed after surgery and oral nerve nutritive drugs (methylcobalamin tablets) can be taken. If the nerve is severed, careful exploration is needed during the operation, nerve suture is carried out, and oral nerve-nourishing drugs are taken after the operation. Numbness of the lower limbs caused by right femur fracture, it is recommended to consult a doctor for timely treatment under the guidance of a physician.