Neuronal migration abnormality refers to various degrees of developmental malformations of the brain tissue during cortical development, including anencephaly-macroglossal gyrus malformation, gray matter heterotopia, schizencephaly, multiple cerebellar gyrus malformations, hemihypophyseal megalencephaly, and localized cortical dysplasia due to various reasons for the obstruction of neuronal cells’ migration from the embryonic germinal matrix to the surface of the brain. Each type has a specific etiology, pathologic changes and imaging features. So, how can neuronal translocation anomalies be prevented? The following are preventive measures for neuronal shift anomalies: Rehabilitation cycles are long, some from childhood to adulthood, and may leave varying degrees of disability. Psychological and financial preparation is needed. If the family’s financial situation is not good, it is best to try to treat the child until he/she is 3 years old. After the brain development is basically completed, it is easier to determine the prognosis, and then you can decide whether to continue the treatment or give up the treatment.