Ankle pain may muscle strain, arthritis, gout, rheumatoid arthritis, for the cause of the drug treatment, physical therapy. 1. Muscle strain: need to reduce walking, avoid standing for a long time, local massage to relax local muscles. 2. Arthritis: non-steroidal anti-inflammatory drugs can be applied, such as diclofenac sodium enteric-coated tablets or ibuprofen extended-release capsules. 3. Gout: local cold compresses, topical diclofenac diethylamide cream, oral febuxostat, reduce the intake of purine food. 4. Rheumatoid arthritis: pay attention to joint warmth, local hot compresses, the application of anti-rheumatic drugs such as leflunomide. The pain in the ankle needs to be examined in the hospital to identify the specific cause of the disease, for the cause of the treatment. The use of drugs need to follow the doctor’s instructions.