Anti-inflammatory drugs with few side effects include penicillin, semi-synthetic penicillins and cephalosporins, among which penicillin has the least side effects and it is generally widely used for upper respiratory tract infections and skin infections. If patients have symptoms such as fever, cough, sputum and sore throat, they can consider applying penicillin for treatment, and it is also effective for tonsillitis. For pregnant women penicillin is a good choice. For patients with impaired liver and kidney function, penicillins can also be chosen, but the dosage should be reduced appropriately according to the degree of liver and kidney damage. Semi-synthetic penicillins can also be chosen. Semi-synthetic penicillins include amoxicillin, meloxicillin, piperacillin, etc. It has a broader antibacterial spectrum than penicillin, and in addition to its effect on Gram-positive cocci, it also has an effect on Gram-negative bacilli and anaerobic bacteria, which means it can be applied to upper respiratory tract infections as well as lower respiratory tract infections, such as patients with pneumonia, can apply semi-synthetic penicillins. There are four generations of cephalosporins, the higher the grade, the broader the antibacterial spectrum, and the stronger the antibacterial strength, so choose the appropriate cephalosporin according to the patient’s needs. If patients are allergic to penicillin and cephalosporin, they can choose macrolides such as azithromycin and erythromycin, but they should pay attention to the damage to the liver. In addition to this, quinolones can also be chosen, but quinolones must be applied only to patients over 18 years of age.