The yellow water and bitter water are considered to be acute cholecystitis or bile reflux esophagitis, etc., which can be treated by diet, medication and surgery under the guidance of a doctor. 1. Acute cholecystitis: Most of the cases are caused by blockage of the gallbladder duct and bacterial invasion, such as gallstones or biliary roundworms, which may lead to blockage of the gallbladder duct, and bacterial infections in the intestines, which may cause acute cholecystitis. Symptoms such as abdominal distension, abdominal pain and vomiting of yellow and bitter water may occur. Cefixime, amoxicillin and levofloxacin can be applied under the guidance of the doctor for treatment, and at the same time pay attention to the diet, eat small meals and try to be light and easy to digest. If there is no relief, it can also be treated by surgery, after which cephalosporin anti-inflammatory drugs can be applied to prevent infection. 2. Biliary reflux esophagitis: it is the reflux of gallbladder and stomach contents into the esophagus, which can easily cause acid reflux, heartburn, and symptoms such as bitter mouth and spitting yellow water, etc. It can be treated with omeprazole, magnesium alumina carbonate, and itopride hydrochloride under the guidance of a doctor. Spit yellow water bitter water, can be under the guidance of the doctor according to the cause of treatment, usually drink more water, eat more fruits and vegetables, eat less stimulating food.