Breast pain is a common complaint in outpatient clinics, which can be classified as cyclic or non-cyclic, or can change from cyclic to non-cyclic. 2/3 of breast pain is cyclic. The vast majority of pre-menopausal women, the most common site of pain in the upper lateral breast, pre-menstrual symptoms worsened. The nature of the pain is distension, heaviness and tenderness. The causes and mechanisms of breast pain are still not fully understood, but psychogenic factors and sex hormone regulation appear to be contributing factors. Breast pain requires treatment refers to the pain affects daily activities, most (85%) of the cases after examination to rule out cancer, after that the pain is relieved, so the pain is better because of the subsidence of the suspicion of breast cancer; the use of tight flat bra 24-hour wear can reduce the pain. Postmenopausal women with hormone replacement therapy may experience breast pain, which can be rapidly improved with non-steroidal painkillers. If the above measures are ineffective, the first choice of drugs for r linoleic acid pills 6 capsules / d, but the effect is slow, need to be 2 ~ 4 months of medication, 70% of the efficacy. The second line of drugs available danazol 100mg/d from the 14th day of menstruation to the 28th day, the effect of the cycle of use is obvious, or triamcinolone acetonide 10mg/d from the end of menstruation to the beginning of the next menstruation, safe, the use of 2-3 cycles of the effect is obvious.