CKD stage 5 has no possibility of cure. CKD is the abbreviation of chronic kidney disease, which can be seen from the name that it is chronic, and once it is involved in chronic disease, there is no possibility of cure. CKD stage 5 is often referred to as the uremic phase, at this stage the kidneys have very little function left and can only be treated with the help of hemodialysis, peritoneal dialysis or kidney transplantation. The kidney transplantation is mainly a cure for this disease, because the removal of toxins is more adequate than the first two treatments, and the patient does not need long-term application of drugs to correct anemia and regulate calcium and phosphorus imbalance, and sometimes the blood pressure control is more stable, from this point of view kidney transplantation can be considered as a cure for this disease, but the kidney transplant patients need to take long-term immunosuppressive drugs, and the patients are prone to serious infections. If the infection is particularly serious, it can lead to death by infectious shock.