Generally a small meatball in the scrotum is an abnormal symptom, which may be a symptom of the manifestation of certain diseases, such as sebaceous cysts, scabies, scrotal eczema and so on. 1. Sebaceous cysts: Due to the obstruction of sebaceous gland excretory ducts, the sebaceous gland cystic epithelium is blocked by the gradually increasing contents and swells to form a retention cyst. Cysts are hemispherical protrusion, smooth surface, hard and tough, the base can be moved, usually no obvious self-conscious symptoms, secondary infection can appear red, swollen, pain and so on. 2. Scabies: a contagious skin disease caused by human scabies mites parasitized on the skin, often occurring in the thin and tender skin, such as finger cracks, wrists, armpits, external genitalia and other parts. Generally manifested as erythema, papules, pimples, and accompanied by intense night itching, the skin may also appear small, raised, grayish-white or light black lines. 3. Scrotal eczema: the scrotum is found densely distributed pinhead to grain-sized papules, papules or small blisters, the base is flushed, may be accompanied by itching. There may be other factors, such as condyloma acuminatum, but this symptom alone is not enough to diagnose the disease. It is recommended that the patient consult a doctor in time to clarify the cause of the disease and give targeted treatment.