Upright deficiency is a common disease in the elderly and children, and according to statistics, about 15% of the elderly over 65 years of age have postural hypotension, which can be as high as 30% to 50% in those over 75 years of age. The gradual hardening of the heart and vascular system in the elderly, as well as the reduction of large-vessel elastic fibers and the enhancement of sympathetic nerves, can cause systolic blood pressure to rise in the elderly. Chronic high blood pressure not only impairs the sensitivity of pressure receptors (located at the carotid artery), but also affects the compliance of blood vessels and ventricles. When there is a sudden change in body position or after taking antihypertensive medication, the risk of ischemia is greatly increased along with a sudden drop in blood pressure. In addition, the poorer ability of the elderly to tolerate hypovolemia may be related to their impaired ventricular diastolic filling. Therefore, any acute illness resulting in excessive water loss, or insufficient oral fluids, or after taking antihypertensive drugs and diuretics, as well as patients who are usually less active and bedridden for a long time, are prone to postural hypotension after standing up. Once postural hypotension occurs, the blood pressure in different positions should be measured repeatedly for clear diagnosis and symptomatic treatment to avoid adverse effects on the patient due to syncope. To check for upright decompensation requires comparative measurement of the patient’s blood pressure in the secluded and seated positions as well as in the standing position. If upright hypotension is found, quickly check for clear presence of tachycardia, altered level of consciousness, pallor, and clammy skin. If all of these signs are present, hypovolemic shock should be considered. Establish large intravenous access for fluid replacement or blood transfusion. Check the patient’s vital signs every 15 minutes and note the volume. History and physical examination: If the patient is not in life-threatening condition, take a medical history. Ask if there is frequent dizziness, weakness, or syncope while standing. Also ask about concomitant symptoms, especially fatigue, terminal breathing, fistula, nausea, headache, abdominal or chest discomfort, and gastrointestinal bleeding. Then ask for a complete medication history. Observe the patient’s skin for swelling. The peripheral pulse beats are palpated, the heart and lungs are auscultated, and finally muscle tone and the patient’s gait are tested for near-stability.