Lipoma is a tumor of normal fat-like tissue, lipoma external medicine has no effect. Lipoma is a common soft tissue benign tumors, mostly in the limbs, trunk and other parts of the body, mainly manifested as a small size of painless lumps, and the boundary is clear, the texture is soft, elastic. In general, lipoma external medicine has little effect and cannot eliminate the lipoma. If the lipoma is limited to the superficial subcutaneous area and has no uncomfortable symptoms, it usually does not need treatment, pay attention to observe its changes and follow the doctor’s instructions to review. If the lipoma is too large or aesthetically displeasing, the patient may be treated with surgery to improve the condition. Except for surgery, any other treatment is not effective for lipoma. Patients are advised to maintain a good mood and healthy lifestyle, actively cooperate with the doctor’s treatment, and pay attention to observe the growth of the lipoma and follow the doctor’s instructions for regular checkups.