Possible clinical causes of acne next to the nose include folliculitis, sebaceous gland duct blockage with infection, and acne. 1. Folliculitis: This condition refers to an inflammatory skin disease in which the hair follicles are mainly involved. Damage to the hair follicles or structural changes in the hair follicles are the causes of folliculitis. Infection of the hair follicles by bacteria is the first cause, and the clinical manifestations are red papules or pustules centered on the hair follicles. 2. Sebaceous gland duct blockage with infection: Sebaceous gland duct blockage is often seen in the skin oil secretion of the situation, which is related to the body’s androgen level is elevated, androgen has the role of stimulating the skin sebaceous gland secretion of oil. When the sebaceous gland ducts are blocked, it is easy to complicate the infection and cause inflammation of the relevant parts of the reaction, the clinical manifestation of the affected areas appear pustules, redness, swelling, pain and other symptoms. 3. Acne: This disease is related to hair follicles being infected by Propionibacterium acnes, and its typical manifestation is that the affected area of the skin is prone to recurrent infections, accompanied by pustules, papules, red nodules, abscesses, etc.; secondly, the elevated level of androgen and the lack of daily cleanliness are also triggering factors. It is recommended that people with this condition should go to the hospital to get a clear diagnosis, so as to carry out targeted treatment.