The effect of pregnancy on the condition of vitiligo has not yet been clearly studied to confirm its relevance. There are many factors that contribute to the development of vitiligo, such as immune factors, psycho-neurological factors, genetic factors, etc., but in most cases, vitiligo is caused by autoimmune disorders and imbalances. Pregnancy may lead to changes in the body’s immune system, the ability to regulate melanin may also change, and the body’s hormone levels will be relatively unstable, so there is a possibility that it may also lead to the expansion of vitiligo. And stopping vitiligo medication during pregnancy can also cause white spots to expand. But also the elevated level of melanocyte stimulating hormone during pregnancy may make the white spots repigmented. Some studies have now found that pregnant women with vitiligo have a significantly increased risk of miscarriage, and that systematic treatment of vitiligo before pregnancy can improve pregnancy outcomes. It is recommended that pregnant women with a history of vitiligo should promptly and actively visit a hospital for diagnosis and treatment.