The treatment of herpes zoster neuralgia mainly relies on oral medication. Topical ointment is mainly for antiviral and infection prevention, such as acyclovir cream, neomycin ointment and lidocaine cream. 1. Acyclovir cream: Herpes zoster neuralgia is caused by viral infection, acyclovir topical application has antiviral effect, can relieve the patient’s neuralgia symptoms. 2. Neomycin ointment: after the herpes zoster blister wall is broken, you can use neomycin ointment to apply externally. Neomycin has a good antibacterial effect, and it has an anti-bacterial effect on the herpes zoster neuralgia area to avoid further aggravation of the pain due to bacterial infection. 3. Compound Lidocaine Cream: It is a local anesthetic itself, which has an anesthetic effect to reduce pain. The mechanism of action is that lidocaine produces analgesia by blocking voltage-gated sodium channels, and the blockage of sodium channels leads to a reduction in ectopic discharge, which in turn inhibits peripheral sensitization. Herpes zoster neuralgia mainly relies on oral medication, patients should go to the hospital in time, under the guidance of the doctor to use the relevant drug treatment.