The third vaccine is usually the Neocoronavirus vaccine. Medications generally do not affect the Neocoronavirus vaccination, but certain diseases may. If the patient’s condition is not under control while taking medication, such as the presence of infections, it is not recommended to receive the Neocoronavirus vaccine, as administering the vaccine in this case may aggravate the adverse effects of the vaccine injection, and it may also lead to an aggravation of the organism’s condition. If the patient’s symptoms have been controlled and the disease has been cured, it is still necessary to decide whether or not the third dose of the New Crown Pneumonia vaccine can be injected according to medical advice. And, before injecting the vaccine, patients need to know the contraindications of the medications they are taking, inform the doctor about the medications they are taking and their personal illnesses, and administer the injection under the doctor’s guidance. Adverse reactions such as itchy skin, nausea and vomiting may occur after the injection of the new crown vaccine. When patients show adverse reactions, they should immediately seek medical attention to clarify the cause of the symptoms so as to avoid significant impact. Tip: The terms “new coronavirus pneumonia and new coronavirus pneumonia” mentioned in this article were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.