Whether or not minimally invasive surgery can be done for subcrestal ventricular septal defects is determined by the degree of the septal defect. Minimally invasive surgery is usually possible for mild subcristal ventricular septal defects, while minimally invasive surgery is not recommended for severe ones. Patients with mild subcrestal septal defects, which have a small diameter and do not involve the valves, can be treated with minimally invasive surgery. Patients with severe subcrestal septal defects, which have a large diameter and may cause discomfort such as chest tightness, dyspnea, and chest pain, are generally not candidates for minimally invasive surgery, and usually require valvular repair of the interventricular septum. Generally patients should eat more high protein, high nutrition, high vitamin food during the treatment period. Pay attention to the prevention of infection, active exercise, enhance body resistance, avoid staying up late and excessive mental stress. Patients with subcristal ventricular septal defects should seek medical treatment in time if they experience any discomfort to avoid delaying their condition.