Gamma globulin is mostly found in human serum and has certain immune effects. high gamma globulin indicates the existence of immune response in the body, mostly due to inflammatory infections, liver damage, hematological diseases and immune diseases. 1, inflammatory infections: mostly seen in various inflammatory diseases, tuberculosis, schistosomiasis and other chronic inflammation or infection. gamma globulin is an important component of human serum antibodies and participates in the body’s immune defense mechanism. When infection occurs in the body, γ globulin content increases and the value will be high; 2, liver damage: staying up late, drinking alcohol and other bad habits may lead to slight damage to liver cells, appearing transient γ globulin high performance, which can mostly be relieved by rest. It can also be seen in autoimmune liver disease, chronic hepatitis, chronic active hepatitis, cirrhosis, alcoholic liver disease, etc. Influenced by the absorption and processing of antigenic substances, humoral immune function is hyperactive, and a large amount of γ globulin is secreted, which can lead to high γ globulin, and the degree of high γ globulin can be related to the severity of liver lesions; 3, hematological diseases: such as multiple myeloma, lymphoma, primary macroglobulinemia, etc., appear Lymphocyte and plasma cell proliferation, the concentration of immunoglobulin in the blood can be increased, resulting in high performance of γ globulin; 4, immune diseases: such as systemic lupus erythematosus, rheumatic fever, rheumatoid arthritis, etc., when autoimmune diseases occur, the patient’s body produces immune response, which can lead to high γ globulin.