Weakness of the legs can be caused by physiological factors, as well as pathologic factors such as spinal cervical spondylosis, trauma, osteoporosis, cerebrovascular disease, endocrine disease, and so on. Physiological factors, such as excessive exercise or fatigue, can cause the symptoms of weak legs. Pathological factors such as spinal cord cervical spondylosis and lumbar spinal stenosis can also cause symptoms due to degenerative changes in the vertebral structure, which compresses or irritates the spinal cord. Fractures, bone fractures or muscle injuries caused by trauma can lead to symptoms of weakness in the legs. Osteoporosis can occur due to elevated nerve excitability and abnormal muscle tissue nutrition. Cerebral hemorrhage and cerebral infarction can occur due to nerve damage or compression. Hyperthyroidism can present the symptom due to low potassium paralysis of the body. Diabetes mellitus can occur due to peripheral neurovascular damage. If you find the symptoms of weak legs, you should go to the regular hospital, after the doctor to identify the cause of the disease, and follow the doctor’s instructions for treatment.