The patient’s eyes appear to be swollen after sleeping, which may be related to physiological factors or due to allergic conjunctivitis, blepharitis, renal impairment disease and other reasons. 1. Physiological factors: If the head is in a low position during sleep or if the patient drinks too much water or uses his eyes excessively before going to bed, it may lead to swelling of the eyes after waking up. 2. Allergic conjunctivitis: When allergic patients’ eyes come into contact with allergens such as mites on the bedding while they sleep, eye allergies such as allergic conjunctivitis may occur, and patients may experience eyelid swelling, as well as itchy eyelids and other uncomfortable symptoms. 3. Blepharitis: Blepharitis refers to suppurative inflammation of the eyelid glands. Under the stimulation of inflammation, the patient may experience redness and swelling of the eyelids, as well as pain in the eyelids and increased eye secretions. 4. Kidney function damage: patients with glomerulonephritis, nephrotic syndrome and other diseases, because of the damage to kidney function, the body water retention, which can lead to eyelid swelling, but also lower limb edema. It is recommended that patients with significant eyelid swelling should consult a doctor in time to assess their condition and follow the doctor’s instructions for treatment.