Patients with symptoms of heartburn can be treated with oral domperidone PAIN, but they need to be combined with acid-suppressing drugs, such as combined with proton pump inhibitors such as omeprazole or rabeprazole, and also combined with H2 receptor antagonists such as ranitidine and nizatidine, in order to have a more satisfactory effect. Mainly the presence of gastroesophageal reflux disease, that is, because of the weakening of the anti-reflux defense mechanism of the esophagus, resulting in bile or gastric contents reflux into the esophagus and cause heartburn symptoms, so in the treatment of the need to use acid suppression drugs combined to promote gastrointestinal peristalsis of the drug. If the effect of taking domperidone tablets is not satisfactory, you can change to take mosapride or cisapride, etc., the specific use of drugs need to consult a specialist. Patients usually need to pay attention to lifestyle changes in life, to lose weight, quit smoking, quit drinking, avoid high fat, chocolate, strong tea and other foods.