There are many reasons why two thighs are hot at night, divided into physiological and pathological reasons, pathological reasons are skin diseases, orthopedic diseases and neurological diseases. 1. Physiological: If you wear leggings or other warming products on your thighs when you sleep at night, the phenomenon of thigh fever will occur, which is a normal physiological phenomenon, and can be restored to normal by removing these warming products, without additional special treatment. 2. Pathological: If you suffer from skin diseases, such as local herpes zoster and dermatitis, the inflammation will cause fever or swelling, pain and other symptoms; there are also cervical spondylosis and lumbar disc herniation and other orthopedic disorders, which will cause local sensory abnormalities through the compression of the nerves to produce this symptom; and there are also neurological disorders, such as peripheral neuritis, which can also be due to sensory abnormalities to produce this symptom. If this phenomenon is suspected to be pathologic, it is recommended to go to the hospital in time.