Maxillary neuralgia belongs to a kind of trigeminal neuralgia, the treatment of choice of drug therapy, drug ineffective can use nerve block therapy, radiofrequency current percutaneous selective thermal coagulation, surgical treatment. 1. Drug treatment: This disease is preferred drug treatment, carbamazepine is currently the first choice of drugs for the treatment of trigeminal neuralgia. Drug treatment must be regular, such as a variety of drug treatment is still ineffective, before considering non-pharmacological treatment. 2. Nerve block therapy: when drug therapy is ineffective or has adverse reactions, and the pain is severe, nerve block therapy is feasible. 3. Radiofrequency current percutaneous selective thermal coagulation: the advantage is that it can selectively destroy the pain fibers of the trigeminal nerve without basically damaging the tactile fibers, which can effectively solve the pain symptoms without affecting facial sensation. The recent efficacy is still acceptable, but it is easy to recur. 4. Surgical treatment: including microvascular decompression surgery, percutaneous puncture radiofrequency destruction, γ-knife radiosurgery . This disease daily should maintain a good mood, regular work and rest, should go to the regular hospital, under the guidance of the doctor to choose the appropriate treatment program.