Anal and vulvar itching, due to different conditions, the medication is different, anal itching may be hemorrhoids, perianal inflammation, vulvar itching may be trichomoniasis, vulvovaginitis, etc., you can be under the guidance of the doctor, through the use of acetaminophen, zinc oxide, metronidazole, cephalosporin and other drugs treatment. 1. Hemorrhoids: the disease is mainly related to diet, defecation habits and other factors, the patient will have anal itching, can be under the guidance of the doctor, through the use of acetaminophen, ibuprofen, hemorrhoidal blood capsules and other drugs for treatment. 2. Perianal inflammation: due to local sweat, secretions, feces and other substances stimulation, resulting in anal itching, need to strictly follow the doctor’s instructions for medication, commonly used drugs are zinc oxide, lidocaine, erythromycin, mupirocin ointment and so on. 3. Trichomonas vaginitis: the disease is mainly caused by Trichomonas vaginalis infection, and unclean sexual behavior, bad habits, etc., resulting in patients with vulvar itching, need to be under the guidance of the doctor, the use of metronidazole, tinidazole and other drugs for treatment. 4. Vulvovaginitis: If it is caused by physical and chemical stimulation, infection, and the specificity of the tissue structure, the patient will have the symptom of vulvar itching, under the guidance of the doctor, the use of cephalosporin, clotrimazole, fluconazole, itraconazole, and other medicines for treatment. It is recommended that patients under the guidance of the doctor, strictly comply with the doctor’s instructions to use drugs, not blindly use drugs or unauthorized changes in drug dosage, in order to avoid the impact on the body.