Exudative changes around both kidneys suggest possible hydronephrosis or renal inflammation. 1. Hydronephrosis: the obstruction of urine discharge due to urinary stones and urinary tumors leads to the increase of intrarenal pressure, which results in exudative changes. In the acute stage, the main thing is to release the obstruction, and at the same time, when there is a combination of infection, antibiotic anti-infection treatment should be used, such as levofloxacin. 2. Kidney inflammation: mostly caused by bacterial infection, may also cause chills, high fever, hematuria and other symptoms. In the acute stage, anti-infective treatment is mainly adopted. Such as levofloxacin and other drugs; if there is a urinary tract obstruction, it is necessary to consider surgical treatment. It is recommended that patients go to the hospital as soon as possible, improve the relevant examination to clarify the diagnosis, follow the doctor’s instructions to standardize the treatment, not self-medication, so as not to delay the condition.