The treatment of ankle fracture may include symptomatic treatment and causative treatment, and the causes of this condition may include medication, osteoporosis, bone tumor and so on. 1. Symptomatic treatment: when ankle fracture occurs, the affected limb needs to be immobilized in a plaster, and the plaster can be changed once after the swelling disappears. Usually it can be healed after 6~8 weeks after the plaster fixation. If the symptoms of ankle pain are serious, you can follow the doctor’s instructions to take oral ibuprofen and other analgesic drugs to relieve pain. In case of severe swelling, elevate the affected limb and apply ice packs, and use anti-swelling agents such as Yunnan Baiyao. 2. Treatment of causes (1) Drugs: Osteoporosis caused by drugs can be stopped or replaced by doctor’s advice, and should not be stopped or replaced privately, so as not to delay the treatment. (2) Osteoporosis: The main treatment is medication, which increases bone density and reduces the risk of fracture through anti-osteoporosis medication, such as zoledronic acid. At the same time, it is necessary to adjust the lifestyle, sunbathing more calcium and vitamin D supplement. (3) Bone tumor: according to the type and stage of tumor, we should choose the comprehensive treatment mainly based on surgery, combined with chemotherapy and radiotherapy. It is recommended to actively seek medical advice and follow the doctor’s instructions for medication and treatment. There may be other reasons for ankle fracture, so it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy.