Gastrointestinal reactions are the most common adverse reactions to chemotherapy in oncology patients, especially to cisplatin-induced gastrointestinal reactions, which are serious in some patients and can make chemotherapy difficult to carry out. It also brings great pain to patients. According to the condition of the disease, the patient’s psychological state and the degree of drug reaction, timely and appropriate treatment can often achieve good results and reduce the patient’s worries: 1, nausea, vomiting, the general use of antiemetic drugs and antiemetic treatment. 2, loss of appetite, is second only to nausea, vomiting gastrointestinal reactions, because the patient does not think about eating, affecting the nutritional intake, so that the patient’s body weakness, reduce the tolerance of chemotherapy, and affect the treatment. Treatment: 1. Give appropriate antiemetic drugs to reduce nausea and vomiting to a minimum and improve the patient’s appetite accordingly; 2. Give megestrol or megestrol at the same time as chemotherapy if necessary to increase appetite, reduce chemotherapy reactions and improve tolerance to chemotherapy; 3. Eat less and more meals and give the patient the food he likes; 4. 5.Provide an environment conducive to eating and avoid contact with cooking odors; 6.Adjust electrolyte balance; 7.Test plasma protein levels; 8.It is appropriate to reduce the dose of chemotherapy drugs in malnourished patients; 9.Give supplemental nutrition via the intestine or outside the intestine when necessary. 3, constipation, because the neurotoxic effect of chemotherapy drugs on the smooth muscle of the gastrointestinal tract, so that the peristalsis is weakened, and then appear intestinal paralysis. Treatment: 1, let the patient eat high-fiber food, drink more water; 2, encourage the patient to move properly; 3, give laxatives to soften the stool; 4, control the number of 5-HT3 antagonist antiemetic drugs; 5, abdominal X-ray examination when needed to understand the functional status of the intestine; 6, reduce the dose of chemotherapy drugs or stop using chemotherapy drugs that cause constipation. 4, diarrhea, because chemotherapy drugs make the gastrointestinal tract epithelial cells damage, increase intestinal peristalsis, affect the absorption of water and nutrients, and diarrhea occurs. Treatment: 1, into low-fiber, high-protein food and supplement sufficient fluids; 2, avoid eating food that is irritating to the gastrointestinal tract; 3, more rest; 4, give anti-diarrheal drugs; 5, intravenous fluid and electrolytes if necessary.