Armpit pain 2 years after lung surgery is usually related to repeated infection, nerve damage and metastasis of cancer cells, which can be treated with medication, surgery and radiotherapy. 1. Repeated infection: if the axillary tissues are infected repeatedly after lung surgery, causing lymph node enlargement, which will cause axillary pain, anti-infection treatment such as penicillin and cephalosporin should be taken according to doctor’s prescription. 2. Nerve damage: lung surgery is relatively traumatic, and the operation may lead to nerve damage, thus causing axillary pain. It can be treated with oral ibuprofen as prescribed by doctor, and if necessary, it can be treated with nutritive nerve drugs such as methylcobalamin orally. 3. Cancer metastasis: If lung cancer patients have axillary pain after surgery, it can also be considered that it is caused by the metastasis of cancer cells spreading to the local area. Local chemotherapy and radiotherapy should be chosen after professional physician’s evaluation to inhibit the progress of cancer cells, and lymph node dissection should be carried out when necessary. If axillary pain occurs 2 years after lung surgery, it is recommended to consult a doctor in time and analyze the cause through imaging examination, tumor marker screening and pathological biopsy before targeted treatment.