The sixth day of coughing sputum from yellow to green, considering the aggravation of the disease, combined with the possibility of Pseudomonas aeruginosa infection, can be given ceftazidime, penicillin and quinolone drugs for treatment. 1. Pseudomonas aeruginosa is a gram-negative bacillus, a bacterium of opportunistic infections, which can be manifested by coughing up yellowish-green sputum. 2. Antibiotics that can be used after Pseudomonas aeruginosa infection include aminoglycoside antibiotics such as gentamicin; quinolones such as ciprofloxacin; and cephalosporins such as ceftazidime. When the condition is aggravated, it is recommended that specialists consult a doctor in a timely manner, need to improve sputum culture and other series of tests, according to the results of the doctor’s orders to adjust the use of medication.