The following drugs can be used for PMS: 1. antidepressants, the first line of treatment for PMS, mainly fluoxetine and clomipramine. 2. anxiolytics, for patients with significant anxiety and prone to irritability, alprazolam. 3. prostaglandin inhibitors, mainly indomethacin. 4. gonadotropin-releasing hormone analogs, also known as GnRHa, which mainly cause a low estrogen state to relieve symptoms and have certain side effects and should not be used for a long time. 5. danazol. 6. The main reason for this is that it causes a low estrogenic state to relieve symptoms and has certain side effects and should not be used for a long time.5. Danazol.6. Bromocriptine.7. Aldosterone receptor antagonists such as spironolactone.8.