Plasminogen activity PTA is an important indicator of exogenous coagulation function, closely related to the severity of the disease, and its low commonly found in patients with hepatitis, to treat the primary disease, if necessary, can be transfused with coagulation factors. Many coagulation factors synthesized in the liver, hepatitis liver disease, coagulation factor synthesis is reduced, prothrombin activity is lower, the normal prothrombin activity of 75% to 100%, acute hepatitis prothrombin activity is less than 40%, suggesting that the severe hepatitis, massive necrosis of hepatocytes, may require artificial liver therapy. Reduced plasminogen activity, bleeding symptoms, through the hemostasis, liver-protecting treatment (such as tranexamic acid, polyene phosphatidylcholine and other drug therapy) after no improvement, can be given to the input of component blood cold precipitation supplementation of coagulation factor therapy, can elevate the plasminogen activity. Low plasminogen activity is often indicative of severe hepatitis, there may also be other diseases, should be actively disposed of treatment, it is recommended that the patient consult the doctor and follow the medical advice.