There is no exact time for cholangiocarcinoma to be formed, which is the time needed for each person with different individual differences, different life style and diet in usual life, as well as different dietary habits. Cholangiocarcinoma is a highly malignant tumor. In the early stage of cholangiocarcinoma, patients do not have special discomfort, which is often found because of checking abdominal CT in the process of physical examination. As the tumor grows, patients may have upper abdominal pain, abdominal distension, nausea and vomiting with jaundice, etc. When accompanied with infection, they may have fever. Cholangiocarcinoma patients need to undergo surgery to remove the tumor, and after surgery with radiotherapy and chemotherapy treatment, which is of certain significance to prolong patients’ life time and improve their quality of life. If the patients have any discomfort, they should go to the hospital in time and avoid carelessness so as not to delay the treatment.