The shots for hand, foot and mouth disease need to be determined according to the different circumstances of each affected child, but in general, the following aspects can be included. First, the first is an antiviral drug, you can choose ribavirin, because the virus of hand, foot and mouth disease is not particularly targeted antiviral drugs, so you can only choose a relatively broad-spectrum antiviral drugs, and ribavirin is one of them, and more commonly used. Secondly, you can inject heat-clearing and detoxifying Chinese medicines, such as Xiyanping or Yansuuning. These two Chinese medicines are also used in children, but because there are no particularly good safety studies on Chinese medicines for clearing heat and detoxifying toxins in children, it is sometimes felt that it is not appropriate to use them. Third, glucocorticoids can also be injected, which are usually applied when the child’s inflammatory response is more pronounced. The child is likely to be seriously ill, and it is likely that other medications than the application of glucocorticosteroids will not control the patient’s temperature and the systemic inflammatory response. Finally, there is the possibility of immunoglobulin injections. Immunoglobulin is a blood product derived from human blood, which can improve the ability to fight diseases in a short period of time, but it is expensive and has the risk of transmitting blood-borne diseases such as hepatitis B, C, AIDS and syphilis. However, it is sometimes necessary to be applied in order to save the life of the child.