Female ankle bone a press a pit, generally due to edema, then you can do according to the following etiology of the corresponding treatment: a, glomerulonephritis: this is given immunosuppressants, hormones, diuretics and other drugs for treatment, specific analysis is as follows: 1, immunosuppressant: commonly used tacrolimus, etc. 2, hormones: commonly used prednisone, methyprednisolone, etc. 3, diuretics: commonly used spironolactone, bicarb, etc., after the above treatment, the symptoms of edema can be improved. After the above treatment, edema symptoms can be improved. Second, hypothyroidism: the treatment is to correct the hypothyroidism, you can apply thyroxine tablets and other drugs for treatment, after the treatment of hypothyroidism is corrected, the symptoms of ankle bone edema disappear. If women have edema of the ankle bone, they can do the above treatment.