With the increase of advanced maternal age, there are relatively more pregnant women at high risk of trisomy 21. The older the mother is, the greater the risk of trisomy 21.
Trisomy 21, also known as Down syndrome, is a common chromosomal disorder. The incidence of trisomy 21 in live births in China is about 1:1000 to 1:600, and the older the mother, the higher the incidence.
In general, the chances of checking for a high risk of trisomy 21 are low in pregnant women under the age of 35, and the chances of checking for a high risk are significantly higher in pregnancies over the age of 35. However, this test is only a rough way of assessing the risk, and even if the test reveals that the pregnant woman is at high risk, it does not mean that the child born is a child with Down syndrome.
Do Down’s screening found to belong to high-risk pregnant women, but also need to do non-invasive DNA, if the results of the test is still high-risk, but also need to further examination, is the amniocentesis test, if the amniocentesis does not find a chromosomal abnormality, indicating that the fetus does not have the possibility of trisomy 21, can be normal delivery. If there is a problem with the amniocentesis, the pregnancy will need to be terminated.
Because children with trisomy 21 are congenitally stupid, there is no cure, so for the sake of eugenics, it is important to do the required labor and delivery tests during pregnancy, but even if the screening is high risk, don’t worry too much, you need to confirm the diagnosis based on the results of further tests.