Stage I Nephropathy is possible to be controlled through active and effective treatment. Most of the Stage I Nephropathy belongs to the benign early stage of Chronic Kidney Disease and the disease progresses slowly. Due to the small kidney damage of the patients, the examination of creatinine may show normal or mildly elevated. Patients with Stage I Nephropathy may usually have symptoms such as positive urine protein and occult blood. To actively treat the primary disease, ACEI or ARB drugs, such as enalapril tablets and irbesartan tablets, can be applied to lower the blood pressure, reduce the urinary protein, and delay the progression of renal function. Therefore, it is possible to control the first stage of kidney disease through active and effective treatment. At the same time, we should try to have a low-salt, low-fat, high-quality and low-protein diet in our daily life, and avoid exertion and infection. Patients with Stage I Nephropathy are advised to go to regular hospitals in time and receive standardized treatment under the guidance of doctors.