If it is a myocardial infarction caused by the blockage of the three main coronary arteries, the scope of infarction is very large, and the mortality rate is very high. It is necessary to go to the hospital immediately for interventional stent implantation, and if there is no interventional surgery, thrombolytic therapy should be started in time, followed by the use of antiplatelet drugs. 1. Interventional stent implantation treatment: patients with symptoms of myocardial infarction, such as severe retrosternal pressure-like pain, dyspnea, etc., ECG St-segment bow-back upward elevation, cardiac enzymes, especially troponin elevation, highly suspicious of coronary heart disease myocardial infarction, the need for immediate interventional therapy, in the clear diagnosis at the same time, can be implanted stents, open the blockage of the coronary artery. 2. Thrombolytic therapy: there is no interventional surgery conditions of the hospital, to start thrombolytic therapy in a timely manner after the infarction, early thrombolytic effect is better, and can reduce the scope of myocardial ischemic necrosis. Commonly used drugs are streptokinase, recombinant human tissue-type fibrinogen activator and so on. 3. Antiplatelet therapy: commonly used drugs include aspirin, Tegretol, etc., which can be taken immediately after infarction and continue to be used for more than 1 year after stent implantation. It can inhibit platelet aggregation, prevent further aggravation of infarction, and also prevent in-stent restenosis. Myocardial infarction is a critical condition, must pay attention to prevention in normal times, especially patients with coronary heart disease, should be under the guidance of specialists to rationalize the use of medication, and at the same time to avoid myocardial infarction triggers.