Wrist pain may be caused by tenosynovitis, or carpal tunnel syndrome, rheumatoid arthritis, etc., which requires medication and surgery. 1. Tenosynovitis: Tenosynovitis is caused by excessive force activities of the wrist joint, such as long time typing, washing clothes and so on. Patients will experience pain in the wrist area and limitation of wrist joint function. If the patient’s local pain is obvious, you can follow the doctor’s advice to use non-steroidal anti-inflammatory drugs, such as ibuprofen, celecoxib and so on. For acute plasma tenosynovitis, it can be treated by incision and drainage. 2. Carpal tunnel syndrome: Carpal tunnel syndrome may be caused by factors such as the lumen of the carpal tunnel becoming smaller, repeated use of the wrist, and an increase in the contents of the lumen. Patients may experience wrist pain, atrophy of the interosseous muscle, numbness of the fingers, and other symptoms, resulting in pain in the wrist area. Patients may be prescribed neurotrophic medications such as methylcobalamin tablets and non-steroidal anti-inflammatory drugs such as ibuprofen and etoricoxib. If medication is ineffective, open carpal tunnel decompression surgery and endoscopic carpal tunnel release decompression surgery are needed. 3. Rheumatoid arthritis: Rheumatoid arthritis is due to genetic, autoimmune, infection and other factors. Patients will have pain in palm and wrist joints, joint stiffness and other manifestations. Patients can use non-steroidal anti-inflammatory drugs such as diclofenac and loxoprofen, and anti-rheumatic drugs such as methotrexate and leflunomide as prescribed by the doctor. For patients with joint deformity, surgery is needed to correct the deformity and restore joint function. It is recommended that patients with wrist pain need to consult a doctor in time to check the cause of the disease, and can take appropriate measures for treatment under the guidance of the doctor.