If there is blood and mucus inside the stool, the most common diseases are ulcerative colitis, Crohn’s disease, intestinal tuberculosis and other diseases such as colon cancer. 1. Ulcerative colitis: also known as chronic non-specific ulcerative colitis, it is a chronic inflammatory bowel disease of unknown etiology. It can lead to damage to the intestinal mucosal barrier under various causes, causing persistent inflammatory damage to the intestinal mucosa, which leads to the phenomenon of blood and mucus in the stool. It can be treated with medications, such as mesalazine, which has a significant anti-inflammatory effect on the inflammation of the intestinal wall. Patients with hemorrhage, perforation, cancer and highly suspected cancer should be treated with surgery, such as total colorectal resection plus ileal storage bag anal canal anastomosis. 2. Crohn’s disease: it is a chronic inflammatory granulomatous disease, a kind of unexplained intestinal disease, which will show symptoms such as abdominal distension, diarrhea, etc. If diarrhea occurs frequently, it will lead to intestinal mucosal congestion and edema, which will cause the phenomenon of bleeding and mucus in the stool. You can choose drugs for treatment, such as azathioprine, mercaptopurine, infliximab and so on. 3. Intestinal tuberculosis: Intestinal tuberculosis is mainly a chronic specific infectious disease caused by Mycobacterium tuberculosis invading the intestinal canal, and symptoms such as abdominal pain, nausea, and blood in the stool will appear after the disease. Generally under the guidance of the doctor to apply anti-tuberculosis chemical drugs, such as isoniazid, rifampicin, ethambutol and other drugs for the treatment of the cell has a significant bactericidal effect. 4. Blood and mucus in stool may be seen in malignant intestinal diseases such as colon cancer, and it is recommended to go to the hospital for professional treatment under doctor’s guidance.