There is a more pronounced proliferation of connective tissue, blood vessels and parenchymal cells such as epithelial cells and glands. Polyps may form in the mucosa. Inflammatory cell infiltration, activation of the mononuclear macrophage system. Fibroblast proliferation can produce a large number of collagen fibers, which can form inflammatory fibrosis, which is more prominent in chronic inflammatory manifestations, even in combination with parenchymal cell proliferation to form inflammatory polyps. The proliferation of parenchymal and mesenchymal cells is the result of stimulation by the corresponding growth factors. There is a relationship with long-term structural abnormalities and tuberculous proliferative lesions. Diagnosis is made by physical examination with gastroscopy and other means. Metaplasia is the result of the direct action of inflammatory factors, or of local circulatory disorders and immune mechanisms mediated by the inflammatory process, as well as the action of the products of the inflammatory reaction profile. The severity of metamorphosis depends on both the nature and intensity of the inflammatory factors and the reactivity of the organism. The hydrolytic enzymes released after the degeneration and necrosis of tissues and cells cause lysis and liquefaction of damaged tissues and cells, and further cause degeneration of surrounding tissues and cells and dysfunction of organs.