Creatinine of about 100μmol / L, lasting for six years, generally less serious, but also need to pay attention to exclude pathological factors. The reference value of creatinine is 53-106 μmol/L for men and 44-97 μmol/L for women. If the patient’s creatinine value is 100 μmol/L, it belongs to the normal range for male patients, and generally does not require special treatment, and can be reviewed regularly; for female patients, it belongs to the category of high creatinine, and needs to be further improved by relevant examinations. Female patients with creatinine 100 μmol / L, lasting six years, considering the possibility of chronic renal failure, but the condition is relatively stable, not serious, but need to improve the relevant examinations to clarify the cause of the disease, if necessary, can be perfected renal puncture biopsy, to assist in the diagnosis of the treatment needs to comply with the doctor’s instructions to strictly control the blood pressure, uric acid, urinary protein, glucose and other indicators, to slow down the progression of the disease. When the patient has a high creatinine, it is recommended to go to the regular hospital in a timely manner, follow the doctor’s instructions to improve the relevant examination and systematic treatment.