Insomnia is an ancient term for “sleeplessness”, which refers to a condition in which sleep is regularly reduced, or it is not easy to fall asleep, or it is easy to wake up after sleep, and it is impossible to fall asleep again after waking up, or even to stay awake all night. The cause of insomnia is mainly due to external sensation and internal injury, which leads to the disorder of the function of the internal organs and the imbalance of qi, blood, yin and yang, resulting in the disturbance of the mind and the spirit and the onset of the disease. Those caused by external sensation are mainly seen in the course of various febrile diseases. Those caused by internal injury, mostly due to violent fright, seven emotions, excessive thinking and brain, depletion of the heart and spleen, or due to deficient endowment, room labor, long-term illness, old age and physical weakness, resulting in heart deficiency and timidity, lack of qi and blood, loss of nourishment of the heart and mind; or yin deficiency and fire, heart and kidney do not intersect, phlegm-heat disturbing the heart and stomach gas, can cause insomnia. Clinically, insomnia can be diagnosed as the main clinical symptom of regular reduction of sleep or difficulty in falling asleep, or waking up easily and not being able to sleep again after waking up. Insomnia is the main symptom of neurasthenia. From the modern medical point of view, it is mainly due to the dysfunction of excitation and inhibition of the cerebral cortex, and mainly due to the weakening of the inhibition function and the corresponding enhancement of the excitation function. In the clinical practice of Chinese medicine, if the evidence belongs to deficiency of qi and blood, deficiency of liver and kidney yin, deficiency of fire and heat disturbing the gods, all of them can be treated with Tune Qi Yang Shen Tang. Adding and subtracting Qi Yang Shen Tang: 24 grams of longan meat, 15 grams of cypress seeds, 15 grams of raw dragon bones (pounded), 15 grams of raw oysters (pounded), 10 grams of Yuan Zhi, 18 grams of raw earth, 12 grams of asparagus, 6 grams of sweet pine, 0.5 grams of mirror vermilion mixed with Fu Shen. Insomnia to qi deficiency is dominant, add fried jujube seeds, astragalus to benefit the qi and calm the mind; blood deficiency manifested very much, add rehmannia, salvia, aconite to nourish the blood and calm the mind; insomnia is heavy, add helianthus bark cypress seeds, mother of pearl to nourish the heart and calm the mind; yin deficiency fire, add Zhi Mu, cypress; dizziness, add ephedra root, floating wheat; dizziness and tinnitus, add magnet, wolfberry.