Stem cell therapy for stroke, which may have some efficacy for some patients, has not yet entered the clinic. Currently, stroke is mainly treated with thrombolysis, endovascular intervention, and antiplatelet aggregation. Stroke is also known as cerebral stroke. The basic mechanisms involved in stem cell therapy for stroke include anti-apoptosis, anti-inflammation, promotion of vascular and neural regeneration, and the formation of new nerve cells and neural circuits. The use of stem cells in the treatment of stroke has been effective, but in some patients the results are not significant. It is still time for stem cell therapy for stroke to enter clinical application, and there are still controversial issues, including the optimal timing of treatment, the number of stem cells, and safety. Therefore, stem cell therapy for stroke is not yet a mature therapeutic technique and still has certain defects. At present, ischemic stroke is mainly treated with thrombolysis, endovascular intervention, and antiplatelet aggregation in the acute phase. After the acute phase, standardized secondary prevention medication should be done, including the use of drugs to control blood pressure, blood glucose, blood lipids and so on. All drugs should be used under the guidance of doctors.