After syphilis is cured, a serologic test for syphilis spirochete antigens can detect positive anti-syphilis spirochete antibodies. After systematic treatment of syphilis, a syphilis spirochete serologic test will detect the presence of syphilis. Syphilis serologic test is a confirmatory test for syphilis. After syphilis spirochetes invade the human body, antibodies to syphilis spirochetes can appear in the serum, and the antibodies can exist for a lifetime, so even after syphilis has been cured, the serologic reaction will remain positive. If the syphilis antibody test is positive, further non-syphilis spirochete antigen serologic test should be carried out, and the change of titer in the non-syphilis spirochete antigen serologic test can be used as an observation of the efficacy of the treatment. A positive syphilis spirochete antibody means that the body is now infected with syphilis and may need to be treated, or that the patient has had a past syphilis infection that has been cured. It is recommended to consult a dermatologic and venereal disease department and keep a good attitude.